The feasibility of miniaturizing the versatile portable speech prosthesis: A market survey of commercial products

The feasibility of a miniature versatile portable speech prosthesis (VPSP) was analyzed and information on its potential users and on other similar devices was collected. The VPSP is a device that incorporates speech synthesis technology. The objective is to provide sufficient information to decide whether there is valuable technology to contribute to the miniaturization of the VPSP. The needs of potential users are identified, the development status of technologies similar or related to those used in the VPSP are evaluated. The VPSP, a computer based speech synthesis system fits on a wheelchair. The purpose was to produce a device that provides communication assistance in educational, vocational, and social situations to speech impaired individuals. It is expected that the VPSP can be a valuable aid for persons who are also motor impaired, which explains the placement of the system on a wheelchair

Alternative strategies for space station financing

The attributes of the proposed space station program are oriented toward research activities and technologies which generate long term benefits for mankind. Unless such technologies are deemed of national interest and thus are government funded, they must stand on their own in the market place. Therefore, the objectives of a United States space station should be based on commercial criteria; otherwise, such a project attracts no long term funding. There is encouraging evidence that some potential space station activities should generate revenues from shuttle related projects within the decade. Materials processing concepts as well as remote sensing indicate substantial potential. Futhermore, the economics and thus the commercial feasibility of such projects will be improved by the operating efficiencies available with an ongoing space station program

A Phenomenological Approach to Understanding the Impact of Chronic Ear Disease on Wellbeing in Young People: Patient and Carer Perspectives.

Background: Chronic Suppurative Otitis Media (CSOM) is a chronic inflammation of the middle ear which usually occurs in childhood. Symptoms of CSOM include ear pain, an odorous discharge and hearing loss, necessitating significant medical intervention. Previous research has largely focused on functional outcomes of CSOM using quantitative methods. Consequently, the lived experience of this condition from patient and carer perspectives is relatively unknown. The aim of the current study is to qualitatively explore the psychological impact of CSOM on young people. Methods: A qualitative semi-structured interview design is proposed. Up to 10 young people aged 12-18 and their primary caregivers will be recruited from local ENT clinics and interviewed individually. Interviews will consider participants’ experience of the meaning of CSOM, its impact on identity and social and emotional aspects of daily life. Interviewing both patients and primary caregivers about the same phenomena will enable triangulation of the data. All interviews will be audio recorded and transcribed verbatim. Data will be analysed using Interpretative Phenomenological Analysis (IPA). Findings: IPA will be conducted on patient and primary caregiver interview data according to the process outlined in Smith, Larkin and Flowers (2009). Initial findings will be shared with the young people and their primary caregivers. Discussion: The findings from the current study will lead to a greater understanding of CSOM on young people’s wellbeing and quality of life. This knowledge will enable ENT clinics and other medical teams to address the psychosocial support needs of this group and ultimately improve patient care

Quality of Life in Adults with Charcot-Marie-Tooth (CMT) Disease: a Photovoice Study

Research has indicated that CMT can negatively affect an individual’s quality of life, particularly their health-related quality of life. However, much of the research which has found this has relied on general questionnaires which are not specific to CMT and therefore may not be assessing what is important to people with CMT. This study aimed to develop an in-depth understanding of the way in which adults with CMT think about their health-related quality of life and the factors which influence this, in order to make recommendations for developing methods of appropriate assessment and intervention

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis.

Background Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating insomnia leads to a reduction in paranoia and hallucinations. Methods We did this single-blind, randomised controlled trial (OASIS) at 26 UK universities. University students with insomnia were randomly assigned (1:1) with simple randomisation to receive digital cognitive behavioural therapy (CBT) for insomnia or usual care, and the research team were masked to the treatment. Online assessments took place at weeks 0, 3, 10 (end of therapy), and 22. The primary outcome measures were for insomnia, paranoia, and hallucinatory experiences. We did intention-to-treat analyses. The trial is registered with the ISRCTN registry, number ISRCTN61272251. Findings Between March 5, 2015, and Feb 17, 2016, we randomly assigned 3755 participants to receive digital CBT for insomnia (n=1891) or usual practice (n=1864). Compared with usual practice, the sleep intervention at 10 weeks reduced insomnia (adjusted difference 4·78, 95% CI 4·29 to 5·26, Cohen's d=1·11; p<0·0001), paranoia (−2·22, −2·98 to −1·45, Cohen's d=0·19; p<0·0001), and hallucinations (−1·58, −1·98 to −1·18, Cohen's d=0·24; p<0·0001). Insomnia was a mediator of change in paranoia and hallucinations. No adverse events were reported. Interpretation To our knowledge, this is the largest randomised controlled trial of a psychological intervention for a mental health problem. It provides strong evidence that insomnia is a causal factor in the occurrence of psychotic experiences and other mental health problems. Whether the results generalise beyond a student population requires testing. The treatment of disrupted sleep might require a higher priority in mental health provision

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

Background Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating insomnia leads to a reduction in paranoia and hallucinations. Methods We did this single-blind, randomised controlled trial (OASIS) at 26 UK universities. University students with insomnia were randomly assigned (1:1) with simple randomisation to receive digital cognitive behavioural therapy (CBT) for insomnia or usual care, and the research team were masked to the treatment. Online assessments took place at weeks 0, 3, 10 (end of therapy), and 22. The primary outcome measures were for insomnia, paranoia, and hallucinatory experiences. We did intention-to-treat analyses. The trial is registered with the ISRCTN registry, number ISRCTN61272251. Findings Between March 5, 2015, and Feb 17, 2016, we randomly assigned 3755 participants to receive digital CBT for insomnia (n=1891) or usual practice (n=1864). Compared with usual practice, the sleep intervention at 10 weeks reduced insomnia (adjusted difference 4·78, 95% CI 4·29 to 5·26, Cohen’s d=1·11; p<0·0001), paranoia (–2·22, –2·98 to –1·45, Cohen’s d=0·19; p<0·0001), and hallucinations (–1·58, –1·98 to –1·18, Cohen’s d=0·24; p<0·0001). Insomnia was a mediator of change in paranoia and hallucinations. No adverse events were reported. Interpretation To our knowledge, this is the largest randomised controlled trial of a psychological intervention for a mental health problem. It provides strong evidence that insomnia is a causal factor in the occurrence of psychotic experiences and other mental health problems. Whether the results generalise beyond a student population requires testing. The treatment of disrupted sleep might require a higher priority in mental health provision